ANNOUNCEMENTS: |
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| 26 Jan: | Look for an email from me with some more useful links. |
| 26 Jan: | Links have been checked and updated. Most (if not all) reserve books should be available by now. |
| 12 Jan: | Remember that there will be no lecture on Tuesday, January 16. Our make-up lecture has been scheduled for Wednesday, January 24 at the usual time and place (5:30-8:20 in Burson 118). This is the day after our regular lecture on Tuesday the 23rd. |
| 12 Jan: | Course Text: Hoffmann, E. d.; Stroobant, V. Mass Spectrometry: Principles and Applications 2nd Ed. (English), New York: Wiley, 2002. ISBN 0-471-48566-7 (paperback, ~$65). A hardcover version of this text (ISBN 0-471-48565-9) is now out of print but may be available used from Amazon.com or elsewhere. |
| 12 Jan: | Welcome to the course! More revisions to come. |
| Past Announcements | |
COURSE MATERIALS:* (posted date: size) |
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| Syllabus: | 6115SyllabusS07.PDF (12 Jan: 51 kB) |
| Special Topics: | 6115SpecialTopicsS07.pdf (12 Jan: 18 kB) |
Departmental MS Instruments: |
UNCCharlotteMS.PDF (12 Jan: 43 kB) |
| Quadrupole Animation: | Quadrupole.AVI (11 Jan: 645 kB) |
| Online Books: (UNC Charlotte users only; please do not "check out.") |
Lee, T. A. A Beginner's Guide to Mass Spectral Interpretation New York: Wiley, 1998. |
| Niessen, W. M. A. Liquid Chromatography-Mass Spectrometry New York: Marcel Dekker, 1999. |
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USEFUL LINKS: |
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| Site: | Description |
| http://www.colby.edu/chemistry/NMR/ NMR.html |
This page, by Thomas Shattuck at Colby College (and despite its NMR title) also includes a number of useful mass spectrometry calculators, including an ESI solvent cluster ion calculator. |
| http://us.expasy.org/ | The Expert Protein Analysis System proteomics server (US mirror from the Swiss Institute of Bioinformatics). Many useful proteomics tools, including oligosaccharide mass calculators for glycopeptides or free glycans. |
| http://prospector.ucsf.edu/ | ProteinProspector set of tools from the UCSF Mass Spectrometry Facility. Excellent peptide fragment mass calculator (among other useful tools). |
| http://www.narrador.embl-heidelberg.de/ | The Protein and Peptide Group at the European Molecular Biology Laboratory. Click on the "Activities" and "PeptideSearch" links. Explains "sequence tags." |
| http://prowl.rockefeller.edu/ | PROWL protein database tools from Rockefeller Recently reformatted and updated. Click on "Chait Lab" for useful MALDI Protocols (including a nice video!) and other information. |
| http://www.matrixscience.com/ | MASCOT protein identification tools from Matrix Science. |
| http://medlib.med.utah.edu/masspec/ | The "Nucleic Acids Masspec Toolbox" by Jef Rozenski. Includes general-purpose molecular weight and elemental composition calculators. Similar tools are available at: http://rna.rega.kuleuven.ac.be/masspec/bamsf_c.htm. |
| http://www.asms.org/whatisms/ | "What is Mass Spectrometry?" Educational pages and links from the American Society of Mass Spectrometry (ASMS). Definitely worth some browsing time! |
| http://www.mc.vanderbilt.edu/msrc/ | [Currently not available.] A very useful general mass spectrometry tutorial (with extensive leading references) and a very nicely illustrated MALDI tutorial (albeit with some information specific to their instrument). |
| http://www.jeolusa.com/ | Inventors of the DART ion source. Click on the link for "Mass Spectrometry" and then on the link (in the left-hand panel) for "Tutorials (Mass Spec)" for a number of very useful documents on mass spectrometry fundamentals. |
| http://webbook.nist.gov/chemistry/ | Useful reference information from NIST, including EI mass spectra and ion thermochemical data. A text MS peak list (mass, intensity pairs) can be obtained for a compound by selecting "Download spectrum in JCAMP-DX format." |
| http://www.webelements.com/ | A very useful web-based periodic table. Click on an element, scroll down to "nuclear properties" and select the link for "Naturally occurring isotopes" to get isotope exact mass and abundance information, as well as a link to a handy isotope pattern calculator. |
| http://base-peak.wiley.com/ | Now a subset of the spectroscopyNOW.com web site. More commercial (and harder to use) than it used to be.... |
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http://www.sciencedirect.com/science/ journal/10440305 |
Online access to the Journal of the American Society of Mass Spectrometry. Available from any campus computer or off campus through the Atkins Library proxy server. |
| This page maintained by: | |
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Dr. Brian T. Cooper
Burson 224 (704) 687-2526 btcooper@uncc.edu B.S.: Purdue University, 1989 Ph.D.: University of Arizona, 1994 Postdoctoral: Iowa State University, 1994-1997 Research Interests: Bioanalytical Chemistry—protein analysis by: Capillary/channel electrophoresis and capillary LC; Ultrasensitive fluorescence detection and imaging; Electrospray and MALDI mass spectrometry. |
Copyright © 2007 Brian T. Cooper.
* Posted course materials are intended for the use of currently enrolled UNC Charlotte
CHEM 6115 students only.
No other use is permitted without the express, written permission of the author.
See Announcements for last modification date.