CHEM 5090. Special Topics in Chemistry. (1-4) Prerequisite: consent of the instructor. Selected topics in chemistry. Lecture and/or laboratory hours will vary with the nature of the course taught. May be repeated for credit. (On demand)

CHEM 5095. Topics for Teachers. (1-4) Prerequisite: consent of the instructor. Selected topics in chemical education. Lecture and/or laboratory hours will vary with the nature of the course taught. May be repeated for credit. (On demand)

CHEM 5111. Instrumental Analysis. (4) Prerequisites: satisfactory score on a chemistry proficiency exam, or consent of the instructor. Selected modern instrumental methods of analysis, including theory and practice, with considerable attention given to the instrument and elementary electronics involved in the techniques. Two lecture hours and six hours of lab per week. (Spring)

CHEM 5121. Advanced Inorganic Chemistry. (4) Prerequisites: satisfactory score on a chemistry proficiency exam, or consent of the instructor. Theoretical inorganic chemistry including the application of physicochemical principles to the study of inorganic systems. Laboratory work involves inorganic preparations and characterization techniques. Three lecture hours and one laboratory period of three hours a week. (Fall)

CHEM 5133. Methods of Organic Structure Determination. (2) Prerequisites: satisfactory score on a chemistry proficiency exam, or consent of the instructor. Study and application of modern techniques, primarily spectroscopy, to determine the structure of organic molecules. One hour of lecture and one laboratory period of three hours each week. (Spring)

CHEM 5134. Organic Reaction Mechanisms. (2) Prerequisites: satisfactory score on a chemistry proficiency exam, or consent of the instructor. Mechanistic and theoretical topics which are beyond the scope of CHEM 2131/2132, including orbital symmetry control of organic reactions, the Hammett Equation and other linear free energy relationships, heterocyclic compounds, polycyclic aromatic compounds, organic photochemistry, carbines, nitrenes, arynes and other short lived, reactive intermediates. (Spring) (Alternate years)

CHEM 5135. Concepts and Techniques in Organic Synthesis. (2) Prerequisite or corequisite: CHEM 5133, satisfactory score on a chemistry proficiency exam, or consent of the instructor. Modern techniques of organic synthesis. Laboratory includes one or more multi-step syntheses of complex molecules. One hour of lecture and one laboratory period of three hours each week. (Spring)(Alternate years)

CHEM 5165. Principles of Biochemistry I. (3) Prerequisite: satisfactory score on an organic chemistry proficiency exam, or consent of the instructor. A study of the structures, properties, and functions of biological molecules, bioenergetics of biological reactions, and enzyme catalysis, with particular emphasis on the underlying chemical principles, including thermodynamics and kinetics. (Fall)

CHEM 5165L. Principles of Biochemistry I Laboratory. (1) Prerequisite or corequisite: CHEM 5165. Physical properties of biological molecules and an introduction to experimental techniques of biochemical research. Eleven four-hour lab periods. (Fall)

CHEM 5166. Principles of Biochemistry II. (3) Prerequisite: CHEM 5165 with a grade of B or better. A study of various metabolic pathways and information transfer including molecular aspects of cell biology and genetics, with particular emphasis on the underlying chemical reactions, including thermodynamics and kinetics. (Spring)

CHEM 5167. Structure and Mechanism in Protein Chemistry (3) Prerequisites: CHEM 5165, and either CHEM 5166 or BIOL 5171, or consent of the instructor. Examination of structures, properties, and functions of proteins, enzyme catalysis, and bioenergetics, emphasizing underlying mechanistic chemical and biochemical principles. (Spring) (Alternate years)

CHEM 5171. Biochemical Instrumentation. (4) Prerequisites: CHEM 5165 and 5165L with a grade of B or better or the consent of the department. Modern instrumental methods used in biorelated areas such as biochemistry, biotechnology and medical technology. Theory and practice. Potentiometry, spectrophotometry, chromatography, sedimentation, and electrophoresis. Two lecture hours and two three-hour laboratory periods per week. (Spring)

CHEM 5175. Physical Biochemistry. (3) Prerequisites: CHEM 5165, 5165L, and 5166, with a grade of B or better, satisfactory score on a physical chemistry proficiency exam, or consent of the instructor. Colloid systems, equilibria in biological fluids, mass and energy transport in fluids and in association with membranes, energy storage and dissipation with relation to specific chemical bonding, enzyme kinetics. (On demand)

CHEM 5185. Chemical Fate of Pollutants. (3) Prerequisites: satisfactory score on chemistry proficiency exam, or consent of the instructor. Chemical reactivity and fate of pollutants (in air, water, soil) in terms of their chemical structure and energetics, mechanisms, structure/energy relationships and their interaction with reactive environmental species including light. (Spring)(Alternate years)

CHEM 5200. Computational Chemistry. (4) Prerequisite or corequisite: satisfactory score on a chemistry proficiency exam, or consent of instructor. Electronic and molecular mechanics-based computational methods, including properties, optimized equilibrium and transition state structures and potential energy surfaces of reactions. Three lecture hours and three hours of laboratory each week. Additional projects required of graduate students. (Fall, Spring)

CHEM 6060. Special Topics and Investigations. (1-3) Prerequisite: consent of the instructor. Directed study of topics of current chemical interest. May be repeated for credit. (On demand)

CHEM 6069. Topics in Biochemistry. (3) Prerequisites: CHEM 6165, or consent of instructor. Discussion of current topics in biochemistry emphasizing their biomedical/biotechnological aspects from bioinorganic chemistry, bioorganic chemistry, bioanalytical chemistry, biophysical chemistry, biocomputational chemistry, biomaterials. May be repeated for credit. Three lecture hours per week. (Spring)

CHEM 6082. Surfaces and Interfaces of Materials Chemistry. (3) Prerequisites: Three semesters of calculus based mathematics (i.e., MATH 1241, 1242, and 2241 and an upper level graduate course in thermodynamics (i.e., CHEM 3142, PHYS 3151 OR MEGR 3112) or departmental approval. Theoretical basis, conceptual understanding and experimental investigations of the properties of surfaces and interfaces of various classes of materials will be presented. The content of this course will build from a rigorous derivation of the physical chemistry of surfaces and interfaces to a discussion of topical materials classes and specific materials properties. Three lecture hours each week. (Alternate years)

CHEM 6101. Biochemical principles. (3) Prerequisites: Consent of instructor. Molecular biophysics of biological molecules. Bioenergetics of biological reactions and enzyme structure, mechanisms, and regulation. Metabolic pathways and the role of cellular organelles. Biochemical analysis methodology. Twenty-three two-hour lectures. (Fall)

CHEM 6115. Advanced Analytical Chemistry. (3) Prerequisite: CHEM 5111 with a grade of B or better, satisfactory score on a chemistry proficiency exam, or consent of the instructor. The application of modern analytical methods to chemical problems. Emphasis is upon the chemical information, particularly structural, obtainable from these techniques. (On demand)

CHEM 6125. Theoretical Inorganic Chemistry. (3) Prerequisite: CHEM 5121 with a grade of B or better, satisfactory score on a chemistry proficiency exam, or consent of the instructor. Group theoretical treatment of current theories of inorganic chemistry. Topics covered: Ligand field theory, molecular orbital theory for complex ions, electronic spectra of complex ions and the magnetic properties of complex ions. (On demand)

CHEM 6126. Organometallic Chemistry. (3) Prerequisites: satisfactory score on a chemistry proficiency exam, or consent of instructor. Previous or concurrent enrollment in CHEM 5133 recommended. Synthesis, structure, characterization, and reactivity of organometallic compounds; introduction to catalysis and bioorganometallic chemistry. Three lecture hours each week. (On demand)

CHEM 6135. Advanced Organic Chemistry. (3) Prerequisite: CHEM 5133 and either 5134 or 5135 with a grade of B or better, satisfactory score on a chemistry proficiency exam, or consent of the instructor. A qualitative discussion of modern mechanistic interpretation of the relations between structure and reactivity. Special emphasis is placed on the role of reactive intermediates such as carbonium ions, carbanions, carbines and radicals. (On demand)

CHEM 6138. Stereochemistry. (3) Prerequisite: Advanced course in Biochemistry or Organic Chemistry. Three-dimensional chemistry and its chemical, physical and biochemical consequences, emphasizing classification of isomers and stereoisomers and the consequences of molecular shape on chemical and biological properties. (Spring) (Alternate years)

CHEM 6145. Chemical Thermodynamics. (3) Prerequisite: satisfactory score on a chemistry proficiency exam, or consent of the instructor. The postulatory basis of classical thermodynamics. Problems in chemical thermodynamics. The use of statistical mechanics for calculating thermodynamic functions. (On demand)

CHEM 6146. Rates and Mechanisms. (3) Prerequisite: satisfactory score on a chemistry proficiency exam, or consent of the instructor. Consideration of chemical kinetics and mechanism schemes, particularly those of current interest. (On demand)

CHEM 6150. Seminar-Internship. (1-3) Prerequisite: consent of the instructor. Required for all teaching assistants. Supervised experience in the teaching of college chemistry. Graded Pass/No Credit. May be repeated for credit. (Fall, Spring)

CHEM 6165. Advanced Biochemistry. (3) Prerequisites: CHEM 6101, BIOL 6102, 6103, 6104, or consent of instructor. Advanced course on protein structure, enzyme and mechanistic biochemistry, metabolic biochemistry, biophysical chemistry. Three lecture hours per week. (Spring)

CHEM 6681. Research Seminar. (1) Prerequisite: consent of the instructor. Discussion of recent developments and special topics in chemistry. Graded Pass/No Credit. (Fall, Spring)

CHEM 6682. Research Seminar. (1) Prerequisite: consent of the instructor. Individual investigation and exposition of the results. May be repeated for credit. (Fall, Spring)

CHEM 6900. Research and Thesis. (1-16) Prerequisite: consent of the instructor overseeing thesis research. Laboratory research for the thesis. (Fall, Spring, Summer)

CHEM 7999. Graduate Residence. (0) Prerequisite: consent of the instructor overseeing thesis research. Required of all master's degree students who are working on a thesis but not enrolled in other graduate courses. (Fall, Spring)

CHEM 8069. Topics in Biochemistry. (3) Prerequisites: CHEM 6165, or consent of instructor. Discussion of current topics in biochemistry emphasizing their biomedical/biotechnological aspects from bioinorganic chemistry, bioorganic chemistry, bioanalytical chemistry, biophysical chemistry, biocomputational chemistry, biomaterials. May be repeated for credit. Three lecture hours per week. (Spring)

CHEM 8101. Biochemical Principles. (3) Prerequisites: Admission to Ph.D. program. Molecular biophysics of biological molecules. Bioenergetics of biological reactions and enzyme structure, mechanisms, and regulation. Metabolic pathways and the role of cellular organelles. Biochemical analysis methodology. Twenty-three two-hour lectures. (Fall)

CHEM 8165. Advanced Biochemistry. (3) Prerequisites: CHEM 8101, BIOL 8102, 8103, 8104. Advanced course on protein structure, enzyme and mechanistic biochemistry, metabolic biochemistry, biophysical chemistry. Three lecture hours per week. (Spring)